TCF7L2 and tauopathy: Dot plots at the pseudobulk level encompassing the entire OL population highlighted a diminished expression of other myelination-related genes, including Mbp, Mag, and Cnp (Fig. 6I), along with myelination-associated transcription factors such as Myrf, Tcf7l2, and Olig2 (Fig. 6J), within the tauopathy-afflicted mouse brain.