CD274 and hepatocellular carcinoma: Thus, we were able to recover the 3D yield distributions of PD-L1 specific fractions of αPDL1–800 (ηT; a parameter to the probe concentration) in HCC tumors and demonstrated superior in vivo quantification of the baseline variations in PD-L1 expression in tumors beyond 5 mm deep in tissue, which could not be achieved by conventional intensity-based optical tomography.