Afterward, 11 ECD-associated genes (ATG5, ATG7, BECN1, CDC42, CDH1, CTNNA1, CYBB, MYH14, RHOA, RNF146, and UVRAG) and 3 ECD-associated lncRNAs (AL157935.2, AC009495.1, and TFAP2A-AS1) were utilized for constructing risk signatures, aiming to predict CM prognosis. Here, CDC42 is linked to cutaneous mastocytosis.