Clinically, double positivity for anti-NMDAR and MOG antibodies is very rare, with an incidence of <10% in patients with anti-NMDAR encephalitis or MOGAD.[10] The incidence of NMDAR positivity in patients with MOG antibody-associated CCE is slightly higher (13%).[7] Double antibody positivity can occur sequentially or simultaneously. This evidence concerns the gene MOG and encephalitis.