ANO6 and central nervous system cancer: [12,13] A previous study has revealed the involvement of ANO6 in blood coagulation and congenital bleeding disorder Scott syndrome.[14] Besides, ANO6 has been reported to participate in cell migration, cell volume regulation, as well as externalization of phosphatidylserine.[15] It has also been demonstrated that ANO6 promoted migration and invasion of glioma cells via regulation of the extracellular signal-regulated kinase signaling pathway.[16] However, the role of ANO6 in BC is still elucidated.