To further investigate the relationship between levels of serum 1,25(OH)2D3 and immunological characteristics in vitiligo, the correlation between serum 1,25(OH)2D3 levels and the three immunological profiles mentioned above were analyzed, and the results shown in Figure 3a–c revealed a significantly negative correlation between 1,25(OH)2D3 and counts of T cells (r = −0.1179, p = 0.0012) and frequency of CD8+ T (r = −0.1734, p = 0.0016) and IFN + CD8+ T cells (r = −0.1895, p = 0.0006). The gene discussed is CD8A; the disease is vitiligo.