SCD and fatty liver disease: On the other hand, the administration of DHA reduced palmitoleic acid and total MUFA in the fetal liver with a higher effect in fetuses from dams fed with an HFD, suggesting that DHA could reduce the activity of SCD1 and protect the fetus from fat accumulation and hepatic steatosis, such as has been shown in obese mice models supplemented with fish oil [49,50].