CLOCK and type 2 diabetes mellitus: Thus, the aim of this study is to evaluate the effects of a nutritional and lifestyle intervention based on nutrigenetic variants in candidate genes (namely, CD36 rs1984112 A>G, CD36 rs1761667 G>A, BMAL1 rs7950226 G>A, CLOCK rs1801260 A>G, CLOCK rs4864548 A>G, and CLOCK rs3736544 G>A) on the anthropometric and clinical parameters of 23 overweight or obese subjects affected by T2D or impaired glucose regulation (IGR) over a one-year period.