Beyond the role of C15:0 as an mTOR inhibitor and AMPK activator, C15:0 supports healthy cellular signaling as a dual partial PPAR α/δ agonist, JAK-STAT inhibitor, and HDAC6 inhibitor, which are well-established moderators of metabolism, lipids, inflammation, and cancer [2,22,24,26,87,88,89]. The gene discussed is HDAC6; the disease is cancer.