HMGCR and myocardial infarction: The present study used In silico molecular docking analyses to investigate the potential interactions between the phytocompounds discovered in NCEE and HMG-CoA reductase, as well as to evaluate the cardioprotective effects of NCEE against ISO-induced myocardial infarction in rats, compared with those of atorvastatin, a typical inhibitor of HMG-CoA reductase in clinical use.