MAP1LC3B and lung adenocarcinoma: Experiments with a lung adenocarcinoma cell line and the autophagy marker protein LC3B (human microtubule associated protein 1 light chain 3), which binds to autophagosomal membranes in its form LC3B-II, showed that the autophagy induction by SPD and SPM only occurred in the presence of active BSAO from supplemental bovine serum.