Nuclear CD25 expression in thyrocytes was significantly higher in patients with thyroid adenoma (p < 0.01), while in inflammatory cells was increased in patients with HT (p < 0.01), the latter result was confirmed at the Mann-Whitney test which showed an increase of this marker in HT compared to cancer (p < 0.01) (Figure 9). The gene discussed is IL2RA; the disease is Thyroid adenoma.