GPT and pancreatitis: For instance, many define the occurrence of these AEs when the leukocyte count is less than 3000/μL, neutrophils < 1500/μL, and lymphocytes < 1000/μL; alanine aminotransferase or aspartate aminotransferase when enzymatic activity exceeds twice the upper limit of the reference range; and for pancreatitis, the occurrence of severe abdominal pain and the three-fold elevation of serum amylase and/or lipase [9,13,25,26,27,32,41].