TGFB1 and breast cancer: Similarly to the previous ones, miRNAs 425-5p and 139-5p are overexpressed in the blood plasma of BC patients, with miRNA-425-5p acting as an oncomiRNA by promoting cell invasion and migration through PTEN, whereas the overexpression of miRNA-139-5p inhibits migration and metastasis (BCSCs related process) by disrupting the TGF-β, Wnt, and MAPK/PI3K signaling pathways [66].