NFKB1 and cancer: Nonetheless, apart from anticancer and cancer-preventive properties, 3′,4′,5,7-tetrahydroxyflavone exhibits the ability to modulate inflammatory processes, as it can regulate differentiated signaling pathways, such as the TLS signaling pathway and NF-κB, as well as suppress proinflammatory mediators, among other things IL-6, IL-8, IL-17, and IL-22 release, and thus has the potential to improve therapies in many medical fields [32].