MAPK6 and cancer: We found that eight cancer-related pathways—TP53, Hippo signaling pathway, WNT signaling pathway, GPCR signaling pathway, Notch signaling pathway, ERBB2 and ERBB4 signaling pathways, MAPK6/MAPK4 signaling pathway, and cell adhesion molecules—were markedly altered in the FOXA1 mutant group, and 132 genes out of 1525 genes were included in these pathways (Figure 2A,B and Table S4).