Nine of the upregulated genes (CD81, EIF4A1, KDM1A, MAOA, METTL3, PDGFB, STEAP1, STEAP2, and TRIM28) identified in FOXA1 mutant prostate cancer, which also overlapped with known oncogenes/driver genes in prostate cancer, were subjected to further exploration of potential therapeutic options. This evidence concerns the gene CD81 and Familial prostate cancer.