TNF and cancer: Several infectious and sterile stimuli have been reported to trigger NET formation including bacteria [10,12], viruses [17], fungi [18,19], parasites [20], pro-inflammatory cytokines like interleukin 8 (IL-8) [21], tumor necrosis factor α (TNF-α) [22], placental micro-debris [23], activated platelets [24], cholesterol crystals, monosodium uric acid [25], immune complexes [26], autoantibodies [27], complements such as C5a [28], and even cancer cells [29,30,31].