Osteoporosis is characterized by the inhibition of the activity of osteoblasts and growth factors, such as: bone morphogenetic protein (BMP), platelet-derived growth factor (PDGF), vascular endothelial growth factor (VEGF), insulin-like growth factors 1 (IGF-1) and fibroblast growth factor 2 (FGF-2) [35]. Here, IGF1 is linked to osteoporosis.