Cytokines and growth factors, such as CXCL12, CCL5, CCL17, IL-8, IL-6, IL-1, IL-2, IL-17, tumor necrosis factor-α, and vascular endothelial growth factor (VEGF), can affect tumorigenic mechanisms in pituitary neoplasms [20]. Here, CXCL8 is linked to pituitary tumor.