The rs1050501 SNP in FCGR2B has notably been shown to be under malaria-driven selective evolutionary pressure [27], and minor allele frequencies of FcγRIIb-232T and FcγRIIIb-HNA1 FCGR variants associated with protection against clinical malaria were reported to be more prevalent in malaria-endemic regions than in non-endemic regions. This evidence concerns the gene FCGR2A and malaria.