FCGR2A and malaria: FcγR recognition of the Fc-domains of antibodies bound to pathogenic antigens leads to immune activation of neutrophils, monocytes, and natural killer (NK) cells, which participate in the elimination of the malaria parasite via antibody-dependent cell phagocytosis (ADCP) and cytotoxicity (ADCC), antibody-dependent cellular inhibition (ADCI), or respiratory burst [10,17,18,19,20].