Indeed, the expression of several miRNAs were inversely correlated with levels of estrogen receptor in human breast cancer (miR-93-5p [36,37]; miR-130a-3p [38,39,40]; and let-7i-5p [41]), and estrogen receptor α was shown to be a direct target of miR-130a-3p [42,43]. Here, ESR1 is linked to breast carcinoma.