PLK1 and cancer: The results of the transwell experiment showed that the downregulation of both UBE2C and PLK1 remarkably suppressed the migration ability in pan-cancer cell lines, compared to that of single-knockdown UBE2C (left to right: p = 0.0120, 0.0274, 0.0338) or PLK1 (left to right: p < 0.0001, =0.0014, 0.0338) (Figure 3B).