PAI-1 is a highly reliable prognostic and biomarker in a host of cancers, including breast [101,102,103,104,105], bladder [106,107], colon [108], gliomas [100,109], ovarian [110,111,112], non-small cell lung cancer [113], and renal [114] cancers. Here, SERPINE1 is linked to non-small cell lung carcinoma.