To evaluate the transcriptome of MYCN-driven neuroblastoma through the course of tumor initiation and progression, we compared bulk mRNA expression profiles of ganglion tissues derived from TH-MYCN+/+ 1 and 2-week-old mice, and tumors from 6-week-old mice, to that of age-matched tissue from wild-type littermates [11]. Here, MYCN is linked to neuroblastoma.