Although this allosteric in silico study by our group was focused on Alzheimer’s disease, the scope can be expanded to include drug candidates targeting multiple SARS-CoV-2 receptors, such as RNA polymerase, main protease, spike protein, ACE2 receptor, and transmembrane protease serine 2 (TMPRSS2). The gene discussed is TMPRSS2; the disease is Alzheimer disease.