According to the ancient books, Cordyceps militaris has the efficacy of relieving coughs, calming asthma, and clearing the lungs and resolving phlegm, and modern pharmacology has also proved that cordycepin was able to suppress the inflammation damage in lungs through the inhibition of various inflammatory pathways such as Nuclearfactor erythroidderived 2-like 2/heme oxygenase-1 (Nrf2/HO-1), NF-κB [15,16,17], and Amp-activated protein kinase (AMPK) [18], to inhibit inflammatory injury in the lungs and exert anti-inflammatory effects in macrophages [19]. Here, HMOX1 is linked to asthma.