We have used HAP1 cells as a model for CML, as HAP1 cells are derived from CML patient cells and have the BCR-ABL gene, which is common in leukaemia’s, turning the myeloid cell into a chronic myeloid cell [34,35], and IFN-I (IFNα2) as a treatment. The gene discussed is BCR; the disease is chronic myelogenous leukemia, BCR-ABL1 positive.