We proposed an interpretable clinical–radiomics model based on both multi-patch radiomics and clinical features, which showed an AUC of 0.822 in the test cohort, higher than the clinical model (AUC: 0.684, p = 0.007), radiomics model (AUC: 0.784, p = 0.415), end-stage liver disease (MELD) score (AUC: 0.529, p < 0.001), and albumin–bilirubin (ALBI) score (AUC: 0.644, p = 0.016). This evidence concerns the gene ALB and End Stage Liver Disease.