Approximately, 60% of ARMS tumors can be characterized by t(1;13) (q35;q14) and the PAX3-FOXO1 fusion protein, while 20% of the ARMS tumors are characterized by t(2;13) (p36;q14) and the PAX7-FOXO1 fusion protein [1,3,4,22,23]. The gene discussed is FOXO1; the disease is alveolar rhabdomyosarcoma.