Guillem et al. investigated MUC gene expression in normal and pre-malignant oesophageal mucosa from 40 surgical specimens in patients undergoing oesophagectomy for Barrett’s oesophagus with OAc, or for OSqCc, and identified that MUC1 and MUC4 were the most frequently expressed mucin genes [35]. Here, MUC4 is linked to Barrett esophagus.