The answer, therefore to targeting the multifaceted functions of SRC-3 in the human organism, is on the one hand a space and time restricted intervention that is focused on the site of the malignant tumor, and on the other hand an intervention that ideally lasts only as long as it is needed for the organism to regain control of the tumor by the restoration of the antitumor immune response. The gene discussed is NCOA3; the disease is neoplasm.