Second, we analyzed the relationship between SOX4 expression and the markers of CD8+ T cells, B cells, neutrophils, macrophages, myeloid dendritic cells, tumor-associated macrophages, monocytes, and natural killer cells, as well as Tfh, Th1, Th2, Th9, Th17, Th22, Treg, and exhausted T cells. The gene discussed is CD8A; the disease is neoplasm.