These were identified as novel translocations: t(11;17)(q13.4;q12), with overlap genes SHANK2 and AP2B1, and t(1;17)(p35.2;q11.2), with the overlap gene NF1, an important tumour suppressor previously reported to be deleted in GI-M-EN cells [52]. The gene discussed is SHANK2; the disease is neoplasm.