EGFR and lung carcinoma: Some of the CD47 correlations identified, such as those between CD47 expression and EGFR mutation, lung cancer stage, and metastasis (see Table 1) can be explained by underlying regulatory mechanisms (i.e., EGFR upregulates CD47 expression as described in Section 4.2., and CD47 promotes lung cancer migration and metastasis, see Section 5.3.2).