Research by Lougaris et al. in 2015 [54], Wehr in 2016 [55], and Wong and Huissoon from 2016 [56] indicate that the percentage of CD8+ T cells showed no significant discrepancy, and similar percentages of other lymphocyte subsets tested were observed between CVID patients with and without CVID cancer. The gene discussed is CD8A; the disease is common variable immunodeficiency.