PTEN and cancer: Moreover, miR-18a (targeting Bcl2l10) [50], miR-550a (targeting the GNE—β-catenin/Wnt pathway) [37], and miR-512 (targeting various MRPS) [51] have been reported to influence both proliferation/apoptosis and invasion/migration/metastasization processes, as well as miR-21 (targeting the hKLF5-PI3K-Akt pathway) [29], miR-155 (targeting PTEN) [52], and miR-873 (targeting TSLC1, among others) [53], whose pleiotropic involvement in various crucial cancer-progression mechanisms (proliferation, angiogenesis, invasion, and metastasis) has been widely reported.