SRF and hepatocellular carcinoma: Of relevance, miR-122 appears also closely related to the prognosis of HCC: decreased miR-122 levels have been associated with cell proliferation, invasion, and metastasis mechanisms, and several targets of miR-122 have been implicated in tumorigenesis, including ADAM10, cyclin G1, SRF, Wnt1, and IGF1R [110].