In particular, miR-550a-5p was shown to promote the proliferation and migration of HCC both in vitro and in vivo in a xenograft tumor model by targeting glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase (GNE) via the Wnt/β-catenin signaling pathway. The gene discussed is GNE; the disease is hepatocellular carcinoma.