Lcn-2, also known as neutrophil gelatinase-associated lipocalin (NGAL), oncogene 24p3, siderocalin, or uterocalin, is a 25 kDa glycoprotein that was initially discovered as part of the innate immune system, but was later discovered to deliver iron to the fast-growing tumor cells within the TME [13,14]. Here, LCN2 is linked to neoplasm.