The activation of caspase-3/7 by auranofin has also been reported in mutant p53 NSCLC cells [30], in p53-null SKOV3 ovarian cancer cells [23], in human gastric cancer cells [55], and in chronic lymphocytic leukemia (CLL) [81]. The gene discussed is CASP3; the disease is B-cell chronic lymphocytic leukemia.