PTCL-NOS with large cells is CD3+, and NK/T-cell lymphoma shows angiocentricity with necrosis with lymphoma cells positive for CD3, CD8, CD56, and cytotoxic markers (TIA-1, granzyme-B, perforin). The gene discussed is NCAM1; the disease is mature T-cell and NK-cell non-Hodgkin lymphoma.