PTCL-NOS is CD3+ in small and large cells, and NK/T-cell lymphoma shows angiocentricity with necrosis with lymphoma cells positive for CD3, CD8, CD56, and cytotoxic markers (TIA-1, granzyme-B, perforin). The gene discussed is GZMB; the disease is mature T-cell and NK-cell non-Hodgkin lymphoma.