Alternatively, fluorescence in situ hybridization (FISH) looking for the t(11;18)(q21;q21)(API2::MALT1) may be helpful for diagnosis since this is the most common genetic alteration in lung MALT lymphoma; however, this translocation is only present in 40–50% of cases (only helpful if it is detected) [21]. The gene discussed is MALT1; the disease is MALT lymphoma.