MALAT1, a type of long non-coding RNA, has been linked to the worsening of ARDS via an increase in ICAM-1 expression as a result of the reduced activity of microRNA-150-5p, implying a possible molecular mechanism for ICAM-1’s role in the development of ARDS [72], which is consistent with the findings of a clinical study on COVID-19, where the elevation of ICAM-1 level was observed in non-survivors [73]. Here, MALAT1 is linked to acute respiratory distress syndrome.