CD8A and neoplasm: Propofol inhibits the synthesis of prostaglandins by canine tumour cells and has no effect on the activity of lymphocytes and natural killer cells [47], as well as on the pro- and anti-inflammatory cytokines [24], reducing variations in the distribution of lymphocytes [145] and having no effect on the ratio of B/T cells and CD3+/CD8+ lymphocytes [82].