Molecular analysis of bovine follicular cyst disease pathogenesis has revealed that ovarian cysts exhibit partial disrupted steroid receptor patterns related to follicle-stimulating hormone receptor (FSHR), progesterone receptor (PGR), LH/choriogonadotropin receptor (LHCGR) and estrogen receptor (ESR) [1,16,17]. Here, ESR1 is linked to Follicular Cyst.