USP39 and cervical squamous cell carcinoma: Based on the results of mRFP-GFP-LC3 adenovirus infection assays, we also found that the reduction in the formation of LC3 punctate induced by SIRT7 silencing was reversed after USP39 or FOXM1 overexpression, suggesting that SIRT7 facilitated the autophagy of cervical squamous cell carcinoma cells via USP39 and FOXM1 (Fig. 7B).