The results of western blot indicated that AAV-ACSM5 significantly increased the protein expression levels of ACSM5 as well as decreased the protein expression levels of FABP4 and PPARγ in mice with LF hypertrophy, and this effect could be reversed by co-treatment of AAV-FABP4 and AAV-ACSM5 (Fig. 5A). This evidence concerns the gene ACSM5 and Lassa fever.