However, there are still some shortcomings in this study, such as the failure to independently verify the role and mechanism of FABP4 or PPARγ in lipid accumulation and fibrosis of LF, and the failure to explore how ACSM5 inhibits FABP4 expression to protect lipid accumulation and fibrosis of LF, which will be the focus of our subsequent studies. The gene discussed is PPARG; the disease is Lassa fever.