Among other cardiometabolic risk factors, higher risk of hypertension incidence [20, 44, 45], metabolic syndrome [40], unfavorable levels of trunk fat [46], insulin [46], HDL [21, 46], left ventricular mass [25, 46], high plasma glucose [20] and incidence of diabetes, in adulthood are significantly associated with higher BMI trajectories during childhood. This evidence concerns the gene INS and diabetes mellitus.