In the pre-matched cohort, the ICU group had significantly more patients who arrived by ambulance; who had total dependence in ADL, severe impairment in consciousness, cardioembolic infarction, atrial fibrillation (AFib), and pneumonia; with mRS score of 0–1 or 0–2 points; who received tPA treatment; and who underwent percutaneous catheter intervention or thrombectomy. The gene discussed is PLAT; the disease is susceptibility to pneumonia measurement.