According to TIMER, samples in Cluster 1 had higher concentrations of B cells, CD4 T cells, neutrophils, macrophages, and myeloid dendritic cells than samples in Cluster 2, as shown in Fig. 3B. Figure 3C shows that samples in Cluster 1 in the MCPcounter database had higher abundance levels of T cells, CD8 T cells, B cells, monocytes, macrophage monocytes, neutrophils, endothelium cells, cancer-related fibroblasts, and myeloid dendritic cells than samples in Cluster 2. Here, CD4 is linked to cancer.