Subsequently, we studied the effects of the presence of DQA1*03:03/DQB1*06:01 (Table 5), DQA1*01:03/DQB1*04:01 (Supplemental Table S10), and DPA1*02:02/DPB1*09:01 (Supplemental Table S11) haplotypes on the prevalence of cardiac phenotypes in patients with CS. The gene discussed is HLA-DPA1; the disease is Cowden syndrome 1.