USP30 and Parkinson disease: To further understand whether USP30 depletion affects the association between pathological αSyn and mitochondria in the PD model, we analyzed the overlap of a mitochondrial marker (OPA-1, red) with phospho-S129-αSyn (green) in the ipsilateral SNpc of the AAV-A53T-SNCA mouse model (Supplementary Fig. 5b).