We next verified that, compared to 50 normal controls, the abundance of METTL3, METTL14, and YTHDF3 was significantly decreased in PBMCs derived from 55 childhood allergic asthma patients, recruited from the Children’s Hospital of Fudan University (Fig. 1g and Supplementary Fig. 3b). The gene discussed is YTHDF3; the disease is allergic asthma.